Maturation of Monocyte-Derived DCs Leads to Increased Cellular Stiffness, Higher Membrane Fluidity, and Changed Lipid Composition
نویسندگان
چکیده
منابع مشابه
Lipid Composition and Membrane Fluidity of Butanol-Tolerant
The effect of butanol challenge (0, 1.0, 1.5% [vol/vol]) and growth temperature (22, 37, 42°C) on the membrane composition and fluidity of Clostridium acetobutylicum ATCC 824 and a butanol-tolerant mutant, SA-2, was examined in chemically defined medium. Growth of strain ATCC 824 into the stationary phase coincided with a gradual increase in the percent saturated to percent unsaturated (SU) fat...
متن کاملLipid fluidity and membrane protein dynamics.
Membrane fluidity plays an important role in cellular functions. Membrane proteins are mobile in the lipid fluid environment; lateral diffusion of membrane proteins is slower than expected by theory, due to both the effect of protein crowding in the membrane and to constraints from the aqueous matrix. A major aspect of diffusion is in macromolecular associations: reduction of dimensionality for...
متن کاملImpaired fetal erythrocytes' filterability: relationship with cell size, membrane fluidity, and membrane lipid composition.
The lipid composition of erythrocytes (red blood cells [RBCs]) plays a significant role in determining certain membrane biophysical properties. We have found that fetal RBCs showed a dramatically low filterability compared with adult RBCs and questioned whether this could be a consequence of their membrane lipid composition. We therefore studied fetal RBCs at two different gestational ages, neo...
متن کاملMaturation State and Function of Monocyte Derived Dendritic Cells in Liver Transplant Recipients
Background: Dendritic cells (DCs) are potent antigen presenting cells for triggering of the immune reaction post transplantation. These cells are centrally involved in the initiation of T cell-dependent immune responses. Objective: To compare the level of DC maturation and function in liver transplant recipients with healthy controls. Methods: In this study, twelve peripheral blood samples we...
متن کاملLipid molecular species retailoring and membrane fluidity.
on cell morphology, i.e. the formation of stomatocytes, when the native mixed-acid PC species in the monolayer are replaced by (1,2-dilinoleoyl)-PC (Fig. 1). This species has a pronounced cone shape because of a larger cross-section at the end of its hydrophobic tails. Consequently, the outer monolayer, and thereby the whole membrane, will bend inwards. Further support for the above hypothesis ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Frontiers in Immunology
سال: 2020
ISSN: 1664-3224
DOI: 10.3389/fimmu.2020.590121